Web24. apr 2024 · a Schematic representation of the promoter region of the SPDEF gene, outlining the putative binding sites for the most relevant transcription factors (STAT6, GFI, … Web10. jún 2013 · We identify prostate-derived ETS factor (PDEF) as a mediator of mammary luminal epithelial lineage-specific gene expression and as a factor required for tumorig …
The MINDy-identified modulators of SPDEF and FOXA1 are …
Web20. dec 2016 · SPDEF and FOXA1 expression and activity in ER+ breast cancer cell lines. (A and B) Relative mRNA expression of SPDEF (A) and FOXA1 (B) in MCF-7, T47D and ZR751 … WebThe MINDy-identified modulators of SPDEF and FOXA1 are frequently altered in breast cancer. (A) Plot from cBioPortal for Cancer Genomics showing the alteration frequency of … covid testing walkertown nc
SPDEF and FOXA1 expression and activity in ER + breast cancer …
Web12. máj 2024 · We show that FOXA1 is essential for the proliferation of HER2+/ER− cells and for the lapatinib-dependent upregulation of numerous genes, including HER3. In a window … Web23. mar 2011 · Spdef inhibited Foxa2 and TTF-1, and induced Foxa3 demonstrating its pivotal role in transcriptional control of airway epithelial cell differentiation. Spdef and Foxa3 were increased after sensitization with pulmonary allergen and were co-localized in goblet cells in normal human bronchial glands and in goblet cells lining airways of patients ... Web20. dec 2016 · We applied the MINDy (Modulator Inference by Network Dynamics) algorithm to four TFs (ESR1, FOXA1, GATA3 and SPDEF) that are key drivers of estrogen receptor … dishwasher cold feed hose connector