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Signal-transducing adaptor protein 2

WebSignal-transducing adaptor protein-2 (STAP-2) is a recently identified adaptor protein that contains a pleckstrin homology (PH), Src homology 2 (SH2)-like domains, and proline-rich … WebSignal-transducing adaptor protein-2 promotes generation of functional long-term memory CD8+ T cells by preventing terminal effector differentiation. Oncotarget. 2024; 8: 30766-30780. Crossref; PubMed; Scopus (7) Google Scholar]. STAP-2 can also bind to FcεRI, which is expressed in mast cells and basophils [46. Sekine Y ;

Pivotal Role of Signal-Transducing Adaptor Protein-2 in ... - PubMed

WebDec 31, 2012 · Fms-like tyrosine kinase 3 (Flt3) is an important growth factor receptor in hematopoiesis. Gain-of-function mutations of the receptor contribute to the transformation of acute myeloid leukemia (AML). Src-like adaptor protein (SLAP) is an interaction partner of the E3 ubiquitin ligase Cbl that can regulate receptor tyrosine kinases-mediated signal … WebMar 29, 2024 · Signal-transducing adaptor protein-1 and protein-2 in hematopoiesis and diseases. These findings indicate an essential role for STAP2 in the generation of a high … darty chateaubriant https://crown-associates.com

Signal-transducing adaptor protein-2 has a nonredundant …

WebOct 19, 2024 · Gαi1/3 is associated with EGF-stimulated EGFR and the adaptor protein Grb2-associated binder 1 (Gab1) to transduce downstream Akt-mTOR activation (Cao et al., 2009). Gαi1/3 are key signaling proteins of vascular endothelial growth factor (VEGF) signaling and are essential for VEGF-induced VEGF receptor 2 (VEGFR2) endocytosis, … WebMar 21, 2024 · STAP2 (Signal Transducing Adaptor Family Member 2) is a Protein Coding gene. Diseases associated with STAP2 include Trichothiodystrophy 1, Photosensitive and … WebDefinition. Adaptor proteins are multi-domain proteins (Fig. 1) that interact with components of signaling pathways [ 1 ]. As a consequence of these interactions, adaptor proteins are able to regulate signaling events within the cell, providing spatiotemporal control and specificity, and influencing how a cell responds to a particular stimulus. bistro the meat 新宿本店

Phosphatidylinositol turnover in receptor mechanism and signal ...

Category:Human Toll/Interleukin-1 receptor domain-containing adapter protein …

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Signal-transducing adaptor protein 2

New insights into posttranslational modifications of proteins …

WebJan 6, 2024 · STAP-2 is a recently discovered adaptor protein that contains a pleckstrin homology domain, an Src homology 2-like domain, and a STAT3-binding region at its C-terminus and plays an important role in a variety of cellular signal transduction pathways by interacting with signaling molecules or transcription factors WebDec 6, 2014 · Previously, we cloned signal-transducing adaptor protein-2 (STAP-2) as a c-fms/M-CSFR interacting protein, and found STAP-2 in T lymphocytes or macrophages is …

Signal-transducing adaptor protein 2

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WebSignal-transducing adaptor protein-2 (STAP-2) is an adaptor protein involved in inflammatory and immune responses, such as inflammatory bowel disease and allergic … WebAn interaction between dysregulated lncRNAs and signal transduction pathways significantly contributes to alteration of cancer glycolysis, thereby promoting or inhibiting ... is a cytoplasmic adaptor protein that amplifies the PI3K signal and plays a critical role in cancer metabolism. 105 Cheng et al demonstrated that lncRNA X ...

WebFGFR substrate 2 (FRS2) is one of the adaptors which binds to the complex, ... BMPs and FGFs are two major signal protein families that share common traits, ... Madshus IH, Sandvig K, Olsnes S. Dual mode of signal transduction by externally added acidic fibroblast growth factor. Cell. 1994 Mar 25;76(6):1039-51. 147 Małecki J, Wesche J ... WebArgBP2 (Arg-Binding Protein 2/SORBS2) is an adaptor protein involved in cytoskeleton associated signal transduction, thereby regulating cell migration and adhesion. These features are associated with its antitumoral role in pancreatic cancer cells.

WebAngiogenesis requires integration of cues from growth factors, extracellular matrix (ECM) proteins, and their receptors in endothelial cells. In the present study, we show that the adaptor protein Sh WebFeb 1, 2024 · Signal-transducing adaptor protein-2 (STAP-2) was discovered as a C-FMS/M-CSFR interacting protein and subsequently found to function as an adaptor of signaling or …

Websignal transduction pathways. Plant Signal. Behav. 2010;5:1370–1378. [15] Schaeffer HJ, Weber MJ. Mitogen-activated protein kinases: specific messages from ubiquitous messengers. Mol. Cell. Biol. 1999;19:2435–2444. [16] Reiser V, Ruis H, Ammerer G. Kinase activity-dependent nuclear export opposes stress-induced nuclear accumulation and

WebSubstrate of protein kinase PTK6. May play a regulatory role in the acute-phase response in systemic inflammation and may modulate STAT3 activity. - MedChemexpress Biology Dictionary bistro theater near meWebMediator of DNA damage checkpoint protein 1 (MDC1) plays a vital role in DNA damage response (DDR) by coordinating the repair of double strand breaks (DSBs). Here, we … bistro the lodge knokkeWebPost-doctoral Fellowship Protein-protein interactions in Signal Transduction 1999 - 2003 Research on ultrasensitive interactions and detailed mapping of various interactions for SH2 and SH3 domains. bistrothekeWebOct 1, 2024 · Signal-transducing adaptor protein (STAP)-2 is one of the STAP family adaptor proteins and ubiquitously expressed in a variety types of cells. Although STAP-2 is … bistro theater göttingenWebApr 15, 2014 · We have recently cloned a novel adaptor molecule, signal-transducing adaptor protein-2 (STAP-2), whose human homolog is identical to a recently cloned … darty châteaubourgWebOct 1, 2024 · Signal-transducing adaptor protein (STAP)-2 is one of the STAP family adaptor proteins and ubiquitously expressed in a variety types of cells. Although STAP-2 is … bistro the knifeWebThe interaction of 3BP2 with LAT is of particular inter- est. LAT was recently isolated as a 36–38 kDa tyrosine- phosphorylated membrane adaptor that recruits various basal activity of two transcription factors involved in signaling proteins, including PLCg1, Grb2, and PI3-K IL-2 gene promoter (i.e., NFAT and AP-1) and, further- upon TCR stimulation (Zhang et al., … bistro the meat 池袋本店