Webb5 apr. 2024 · Liu et al. discovered that MUC19 could upregulate AFP expression in GC cells and promote the development of hepatoid adenocarcinoma of the stomach (HAS). 37 In this study, we found that DKK1 was associated with AFP expression in AFPGC by combining single-cell and TCGA transcriptomic data, which was further confirmed by a … Webb21 nov. 2024 · Recent advances in the technologies involving tissue dissociation and high-throughput sequencing at a single cell level have enabled the generation of single cell RNA sequencing (scRNA-seq) datasets, which have been …
Heterogeneity of immune cells in human atherosclerosis revealed …
Webb12 apr. 2024 · Peripheral artery disease (PAD) commonly refers to obstructive atherosclerotic diseases of the lower extremities and affects approximately 8.5 million people in the United States and 200 million people worldwide (1, 2).Approximately 5 to 10% of patients with PAD progress to critical limb-threatening ischemia at 5 years (), with … Webb19 nov. 2024 · ScRNA (Mieth et al., 2024) uses non-negative matrix factorization to incorporate information from a larger annotated dataset and then applies transfer … sunova koers
Alignment comparison of cell embeddings across data sets
Webb21 maj 2024 · Tumor-infiltrating myeloid cells (TIMs) comprise monocytes, macrophages, dendritic cells, and neutrophils, and have emerged as key regulators of cancer growth. … Webb19 mars 2024 · We preprocess scRNA-seq data as commonly done following steps mostly inspired by Seurat [ 34] in the implementation of Scanpy [ 35 ]. These steps consist in basic filtering of the data, total count normalization, log1p logarithmization, extraction of highly variable genes, a potential regression of confounding factors, and a scaling to z -scores. Webb5 sep. 2024 · We examined whether specific ligand-receptor pairs could inform the pathophysiological response that drives the cellular organization of the GIMATS module, … sunova nz