Phf1 protein

Author: ahnu

August undefined, 2024

WebSubcellular - PHF1 - The Human Protein Atlas SUMMARY TISSUE BRAIN SINGLE CELL TISSUE CELL PATHOLOGY DISEASE IMMUNE BLOOD SUBCELL CELL LINE STRUCTURE … Web21. dec 2012 · The equilibrium between self-renewal and differentiation of hematopoietic stem cells is regulated by epigenetic mechanisms. In particular, Polycomb-group (PcG) proteins have been shown to be ...

Ezh2 requires PHF1 to efficiently catalyze H3 lysine 27 ... - PubMed

WebPHF1. General description of the gene and the encoded protein (s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project. Official gene symbol, which is typically a short form of the gene name, according to HGNC. Full gene name according to HGNC. WebProtein (PHF1) Transcript and protein aligned (ENST00000374516.7+PHF1) Gene fusions PHF1 is involved in 3 fusions, with the following genes: JAZF1 (5 mutations in 45 samples) MEAF6 (4 mutations in 8 samples) EPC1 (1 mutation in 1 sample) Drug sensitivity data n/a External links Links to bioinformatics resources that are related to PHF1. OMIM rna 260 280

PHF1 fusions cause distinct gene expression and chromatin …

Web27. júl 2024 · PHF1 [plant homeodomain (PHD) finger protein 1], which contains two kinds of histone reader modules, a Tudor domain and two PHD fingers, is an essential factor for … WebThe protein is a component of a histone H3 lysine-27 (H3K27)-specific methyl transferase complex, and functions in transcriptional repression of homeotic genes. The protein is … WebPHF1 is part of cluster 72 Non-specific - Transcription with confidence i Confidence is the fraction of times a gene was assigned to the cluster in repeated clustering, and therefore … teresa miralles valls

Pathologically phosphorylated tau at S396/404 (PHF-1) is …

PIF1 Gene - GeneCards PIF1 Protein PIF1 Antibody

WebA polycomb group protein, PHF1, is involved in the response to DNA double-strand breaks in human cell. 45: 24285434: 2014: Novel ZC3H7B-BCOR, MEAF6-PHF1, and EPC1-PHF1 fusions in ossifying fibromyxoid tumors--molecular characterization shows genetic overlap with endometrial stromal sarcoma. 30: Web11. jan 2011 · According to another report, PHF1 recruits the PRC2 complex at double-strand breaks (DSBs) and inhibits the activity of PRC2 ( PubMed: 23142980 ). Regulates … teresa looneyWebThe mammalian Polycomblike protein PHF1 was previously shown to interact with the Polycomb group (PcG) protein Ezh2, a histone methyltransferase whose activity is pivotal … teresa miller

"Web15. dec 1994 · The present study extends this observation by showing that PHF-1 recognizes tau peptides containing either individually phosphorylated Ser396 or Ser404, … " - Phf1 protein

Phf1 protein

PHF1 PHD finger protein 1 [ (human)] - National Center for …

Web9. mar 2024 · Phf1 PHD finger protein 1 [ (house mouse)] Gene ID: 21652, updated on 9-Mar-2024. Summary. The protein encoded by this gene belongs to the polycomb-like protein family, which is a component of polycomb repressive complex-2. This complex represses gene expression by catalyzing the trimethylation of histone H3 lysine 27 and is required … This gene encodes a protein with significant sequence similarity to Drosophila Polycomblike. The encoded protein contains a zinc finger-like PHD (plant homeodomain) finger which is distinct from other classes of zinc finger motifs and which shows the typical Cys4-His-Cys3 arrangement. PHD finger genes are thought to belong to a diverse group of transcriptional regulators possibly affecting eukaryotic gene expression by influencing chromatin structure. Two transcript variants …

Did you know?

Web10. jan 2006 · Similar Proteins; Q8GYE0 · PHF1_ARATH. Protein. SEC12-like protein 1. Gene. PHF1. Status. UniProtKB reviewed (Swiss-Prot) Organism. Arabidopsis thaliana (Mouse … Web31. jan 2024 · The p75 isoform, also known as lens epithelium derived growth factor (LEDGF), is a chromatin-associated protein involved in cancer, auto immune diseases, HIV pathogenesis, and cell survival. LEDGF/p75 facilitates HR in S- and G2-phase cells and depletion of p75 sensitizes cells to ionizing radiation, camptothecin and mitomycin C [ 43 ].

Web21. mar 2024 · PHF1 (PHD Finger Protein 1) is a Protein Coding gene. Diseases associated with PHF1 include Ossifying Fibromyxoid Tumor and Endometrial Stromal Nodule . Among its related pathways are RNA Polymerase I Promoter Opening and Gene expression … WebGeneral description of the gene and the encoded protein (s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project. Human …

Web9. aug 2024 · To determine whether PHF1 is an epigenetic regulator with clinical significance, we firstly conducted the differential analysis in TCGA-LUAD ( N = 483) and … Web23. okt 2024 · PHF1, a PRC2 accessory protein of the Polycomblike family, extends PRC2 residence time on DNA and chromatin. Crystallographic and functional studies reveal that Polycomblike proteins contain...

WebPHF1 Interacts with CRL4B and PRMT5–WDR77 Complex. (A) Immunoaffinity purification of PHF1-containing protein complexes. Cellular extracts from HEK 293T cells stably …

Web1. former designation for biotin; 2. vitamin B12 analogue or precursor; 3. a glycoprotein that regulates the activity of complement factor C3b; a deficiency results in the lack of … rna 260/280比值Web3. dec 2024 · We show that SCRN1 is a neuronal protein that abundantly accumulates in NFTs and plaque associated dystrophic neurites throughout the progression of AD and in DS and PART. Surprisingly, SCRN1 did not co-localize with pTau-positive glial or neuronal inclusions in CBD, PSP or PiD. teresa medina minneapolis mnWebPHF1 (HGNC Symbol) Synonyms: MTF2L2, PCL1, TDRD19C: Description: PHD finger protein 1 (HGNC Symbol) Entrez gene summary: This gene encodes a Polycomb group protein. … rn61981 jeans