WebAmong patients with Parkinson's disease, the prevalence of major depression has been reported as 7.7% to 38% 48–50; that of minor depression, 10% to 32% 48, 50; and that of general depressive symptoms, 34% to 47%. 49, 51–55 Depression in Parkinson's disease is associated with less self-punitive ideation, more anxiety, dysautonomia, and greater … WebRaja K, Ramrakhia S, Dev K, et al. (September 30, 2024) The Risk Factors for the Wearing-Off Phenomenon in Parkinson's Disease. Cureus 12(9): e10729. DOI 10.7759/cureus.10729. Materials And Methods This observational, cross-sectional study was conducted from April 2024 to Dec 2024 in the Neurology
The levodopa wearing-off phenomenon in Parkinson’s disease ...
WebIt was the aim of our study based on a group of 460 patients suffering from Parkinson's disease to find out possible pathogenetic linkups for the so-called "on-off" phenomenon. … Web29 de jun. de 2006 · An appreciation of the changing response to levodopa over time and an understanding of the pharmacokinetic principles underlying the development of complications such as wearing-off is essential in the long-term management of the patient. Levodopa is the most efficacious treatment in the management of Parkinson’s disease. … mary grace solenad
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Web10 de abr. de 2024 · Background: Freezing of gait (FOG) is a common disabling symptom in Parkinson’s disease (PD). Cognitive impairment may contribute to FOG. Nevertheless, their correlations remain controversial. We aimed to investigate cognitive differences between PD patients with and without FOG (nFOG), explore correlations … WebAbstract. Wearing-off phenomenon that complicates levodopa therapy of Parkinson's disease has been attributed to a reduction in striatal dopamine storage due to the … Web22 de abr. de 2024 · The wearing-off phenomenon is an end-of-dose deterioration that is closely related to levodopa intake periods; associated fluctuations occur whose latency progressively decreases as the disease progresses. Behavioral on-off symptoms: These would be the neuropsychiatric manifestations associated with motor on-off phenomena. mary grace sm bicutan