Dsc3 and cancer
WebDesmocollin 3 (DSC3) is a desmosomal cadherin that is required for maintaining cell adhesion in the epidermis as demonstrated by the intra-epidermal blistering observed in Dsc3 null skin. Recently, it has been suggested that deregulated expression of DSC3 occurs in certain human tumor types. WebA 76-year-old Japanese man presented with a 6-year history of a sore throat. He was treated at several clinics without any improvement before being referred to us. Physical examination revealed widespread erosions and ulcers from the palate to the larynx. Approximately 25 × 15 mm in size, erosive lesions were present on the …
Dsc3 and cancer
Did you know?
WebDownload scientific diagram DSC3 gene expression is silenced or greatly reduced in a high percentage of breast tumor cell lines. DSC3 expression relative to human mammary epithelium cells (HMECs ... WebMar 24, 2014 · Desmocollin 3 (DSC3) was found to be frequently down-regulated in several cancers such as breast, oral, colorectal and lung cancer, and inactivation of DSC3 in …
WebMay 14, 2014 · Regulation of Desmocollin3 Expression by Promoter Hypermethylation is Associated with Advanced Esophageal Adenocarcinomas Authors Qinggang Wang 1 , DunFa Peng 2 , Shoumin Zhu 2 , Zheng Chen 3 , TianLing Hu 2 , Mohammed Soutto 2 , Rama Saad 4 , Shutian Zhang 5 , Wael Ei-Rifai 6 Affiliations 1 1. WebAug 21, 2024 · Abstract Desmocollin 3 (DSC3) is a transmembrane adhesion protein of desmosomes and involved in carcinogenesis in various cancer types. Downregulation of DSC3 has been reported in colorectal...
WebExpression of DSC3 is used as a diagnostic biomarker to differentiate squamous NSCLC from adenocarcinoma of lung. DSC3 expression is also seen in ovarian cancer, melanoma, colorectal cancer, cervical cancer, and meningioma cancer arising from oral cavity. Expression of wild type p53 is associated with expression of DSC3. WebMar 24, 2014 · Desmocollin 3 (DSC3) was found to be frequently down-regulated in several cancers such as breast, oral, colorectal and lung cancer, and inactivation of DSC3 in these cancers was caused by …
WebSuggest that Dsc3 can mediate FSH-induced ovarian cancer cell proliferation by activating the EGFR/Akt signaling pathway. data suggests that DNA methylation …
WebA nonsense mutation in the DSC3 gene (600271.0001) mapping to chromosome 18q12.1 was identified in the consanguineous Afghan family with hypotrichosis and … how much money does tenz make a yearWebDec 1, 2024 · Desmocollin-3 (DSC3) is DSC3 protein coding gene, expressed in some epithelial cancers. DSC3 expression has prognostic value in some cancers. Using … how do i remove ink stainsWebDSC3 INFORMATION. Proteini. Full gene name according to HGNC. Desmocollin 3. Gene namei. Official gene symbol, which is typically a short form of the gene name, according to HGNC. DSC3 (CDHF3, DSC, DSC1, DSC2, DSC4) Protein classi. Assigned HPA protein class (es) for the encoded protein (s). how do i remove internet explorer 11Webferentiated layer, whereas Dsg3, Dsc2, and Dsc3 show the highest expression in the basal proliferative layer (for more detail see previous reviews in this series Berika & Garrod, 2014; Harmon & Green, 2013). In cells express-ing an overlapping pattern of desmosomal cadherins, dif-ferent Dsgs and Dscs can also be detected in individual how much money does taysom hill makeWebSep 25, 2015 · In breast cancer, the metastasis suppressor genes desmocollin 3 (DSC3) and MASPIN, for instance, were reported to be frequently silenced by an epigenetic mechanism . DSC3 is a glycoprotein, belonging to the cadherin superfamily, required for the desmosome-mediated cell-to-cell junction and adhesion ( 81 ). how much money does tax take off on paycheckWebcancer expression of DSC3 is seen at basal layers of tumor. DSC3 Abstract Desmocollin-3 [DSC3] is a transmembrane glycoprotein belonging to cadherin family of homophilic … how much money does tft makeWebOver 100 cadherins have been identified and they are mainly divided into four groups: classical cadherins (CDHs), protocadherins (PCDHs), desmosomal (DSC), and cadherin-related proteins. Accumulating evidence has indicated that several members of the cadherins are involved in breast cancer development. how much money does tee grizzley have