Ctsh protein

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August undefined, 2024

WebInterestingly, the CTSH protein expression data support the clinical observation that the TT genotype differs from the CC and CT genotypes. The lack of association between CTSH … WebThe protein expression overview (Figure 7B) suggested that higher expression appeared in prostate cancer, thyroid cancer and renal cancer. Among human cancers, both mRNA …

CTSB is a negative prognostic biomarker and therapeutic target ... - Nat…

WebCathepsin H (CTSH) is a type 1 diabetes (T1D) risk gene; large-scale genetic and epidemiological studies found that T1D genetic risk correlates with high CTSH … WebCTSH; cathepsin H; Description From CBI Gene: The protein encoded by this gene is a lysosomal cysteine proteinase important in the overall degradation of lysosomal … dewalt battery powered hand vacuum

Pancreatic beta cell autophagy is impaired in type 1 diabetes

WebView mouse Ctsh Chr9:89936320-89958148 with: phenotypes, sequences, polymorphisms, proteins, references, function, expression WebCTSH: Pro-cathepsin H; Important for the overall degradation of proteins in lysosomes; Belongs to the peptidase C1 family (335 aa) ... Pulmonary surfactant-associated protein … WebCTSH INFORMATION. Proteini. Full gene name according to HGNC. Cathepsin H. Gene namei. Official gene symbol, which is typically a short form of the gene name, according to HGNC. CTSH (ACC-4, ACC-5, ACC4, ACC5, CPSB) Protein classi. Assigned HPA … Expression of CTSH (ACC-4, ACC-5, ACC4, ACC5, CPSB) in amygdala … Expression of CTSH (ACC-4, ACC-5, ACC4, ACC5, CPSB) in pancreas … Expression of CTSH (ACC-4, ACC-5, ACC4, ACC5, CPSB) in midbrain tissue. … Expression of CTSH (ACC-4, ACC-5, ACC4, ACC5, CPSB) in rectum tissue. … Expression of CTSH (ACC-4, ACC-5, ACC4, ACC5, CPSB) in thyroid gland … GTEX-XYKS-2726-SM-4E3IC: 60-69 years, female: 93.2: GTEX-13OVL-0326-SM … Expression of CTSH (ACC-4, ACC-5, ACC4, ACC5, CPSB) in fallopian tube … Expression of CTSH (ACC-4, ACC-5, ACC4, ACC5, CPSB) in skin tissue. … Smooth Muscle - CTSH protein expression summary - The Human Protein Atlas Expression of CTSH (ACC-4, ACC-5, ACC4, ACC5, CPSB) in stomach tissue. … church lane wistaston

CTSH Gene - GeneCards CATH Protein CATH Antibody

Pharos : Target Details - CTSH - National Institutes of Health

WebImportant for the overall degradation of proteins in lysosomes. The protein encoded by this gene is a lysosomal cysteine proteinase important in the overall degradation of lysosomal proteins. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. The encoded protein, which belongs to the peptidase … WebFurthermore, the up-regulation of the CTSH protein in HepG2 cells after IR gave us a definitive answer to explain the phenomenon that the HepG2 cell was more resistant to radiation than the MHCC97H cell, in which the CTSH expression did not increase as significantly as in the HepG2 cell (Figure 2 e,i,j). From this perspective, we found a novel ... church lane withernwickWebFeb 4, 2024 · Proteome-wide association studies (PWASs) of AD found that variants rs12148472 and rs34593439 in the CTSH gene were associated with the CTSH protein … church lane wirral

"WebCTSH. The protein encoded by this gene is a lysosomal cysteine proteinase important in the overall degradation of lysosomal proteins. It is composed of a dimer of disulfide … " - Ctsh protein

Ctsh protein

Protein structure - CTSH - The Human Protein Atlas

WebMar 9, 2024 · Furthermore, the up-regulation of the CTSH protein in HepG2 cells after IR gave us a definitive answer to explain the phenomenon that the HepG2 cell was more resistant to radiation than the MHCC97H cell, in which the CTSH expression did not increase as significantly as in the HepG2 cell (Figure 2e,i,j). From this perspective, we … WebCTSH. HGNC Family. Minor histocompatibility antigens, Cathepsins (CTS) Name. cathepsin H. Description. The protein encoded by this gene is a lysosomal cysteine proteinase important in the overall degradation of lysosomal proteins. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor.

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WebNM_004390.5(CTSH):c.785A>G (p.Tyr262Cys) AND Inborn genetic diseases Clinical significance: Uncertain significance (Last evaluated: Dec 21, 2024) Review status: 1 star out of maximum of 4 stars WebNM_004390.5(CTSH):c.296C>T (p.Pro99Leu) AND Inborn genetic diseases Clinical significance: Uncertain significance (Last evaluated: Nov 29, 2024) Review status: 1 star out of maximum of 4 stars

WebProtein structure for human protein CTSH (ACC-4, ACC-5, ACC4, ACC5, CPSB) We use cookies to enhance the usability of our website. If you continue, we'll assume that you … WebThe protein encoded by this gene is a lysosomal cysteine proteinase important in the overall degradation of lysosomal proteins. It is composed of a dimer of disulfide-linked …

WebFrom CBI Gene: The protein encoded by this gene is a lysosomal cysteine proteinase important in the overall degradation of lysosomal proteins. It is composed of a dimer of … WebJan 30, 2024 · Another type 1 diabetes susceptibility gene, Cathepsin H (CTSH) [36, 37], is a lysosomal cysteine protease that is crucial for lysosomal protein degradation. Importantly, the CTSH susceptibility allele is associated with faster disease progression in newly diagnosed diabetes and reduced beta cell function in healthy humans .

WebCathepsin H. Cathepsin H is a protein that in humans is encoded by the CTSH gene. [5] [6] The protein encoded by this gene is a cysteine cathepsin, a lysosomal cysteine …

WebMar 11, 2024 · Cathepsin B (CTSB) is an exclusive multifunctional protein of cysteine protease family in that it has an additional pH sensitive occluding loop which allows it to … dewalt battery powered hand grinderWebSep 1, 2024 · The CTSH protein expression exerted no . tissue speci city (Figure 6B). Besides the expression overview in normal tissue, the . abnormal expression of CTSH in cancer tissues was also . church lane witneyWebNM_004390.5(CTSH):c.20T>C (p.Leu7Pro) AND Inborn genetic diseases Clinical significance: Uncertain significance (Last evaluated: Mar 23, 2024) Review status: 1 star out of maximum of 4 stars church lane wishawWebThe cytoskeletal protein talin, an actin- and β-integrin tail-binding protein, plays an important role in cell migration by promoting integrin activation and focal adhesion formation. Here, we show that talin is a substrate for cathepsin H (CtsH), a lysosomal cysteine protease with a strong aminopeptidase activity. Purified active CtsH sequentially cleaved … dewalt battery powered grease gun lowesWebApr 20, 2024 · Ctsh protein seemed decreased in EA lungs compared with age-matched control. (C,D) Representative immunoblotting and densitometric analysis of Bmp4 and Ctsh protein expression in fetal … dewalt battery powered hammer drillWebMar 21, 2024 · Go to Variation Viewer for CTSH variants; Summary. The protein encoded by this gene is a lysosomal cysteine proteinase important in the overall degradation of … church lane woodchurch postcodeWebSymbol: Ctsh: Name: cathepsin H: RGD ID: 2447: Description: Enables aminopeptidase activity; kininogen binding activity; and protein self-association. Involved in ... church lane wivelsfield