WebCLEC2 family members have broad tissue expression, with LLT1, AICL and KACL expressed on B cells, monocytes, and keratinocytes, respectively (3-5). In contrast, CLEC2L, a homodimeric cell surface receptor, is predominantly expressed in the brain and is referred to as the brain-associated C-type lectin (BACL) (6). Mature human CLEC2L … WebJan 5, 2015 · CLEC2 is also a receptor for the endogenous platelet activator podoplanin (PDPN; 608863). Using protein binding experiments, Suzuki-Inoue et al. (2010) found …
CLEC2A: a novel, alternatively spliced and skin-associated member …
WebC-type lectin domain family 1 member B (UniProt Q9P126; also known as C-type lectin-like receptor 2, CLEC-2) is encoded by the CLEC1B (also known as CLEC2, UNQ721/PRO1384) gene (Gene ID 51266) in human. CLEC-2 is a type II single-transmembrane (a.a. 34-54) protein with a large extracellular (a.a. 55-229) region that … WebJun 3, 2024 · CLEC5A and CLEC2 are spleen tyrosine kinase (Syk)-coupled C-type lectin receptors, abundantly expressed by leukocytes and platelets, respectively. Whereas CLEC5A is a pattern recognition receptor... effeminate used in a sentence
Fawn Creek Township, KS - Niche
WebThe most recent addition to the human CLEC2 family is keratinocyte-associated C-type lectin (KACL or CLEC2A), whose expression is almost exclusively restricted to the skin, in marked contrast to the broad expression of other CLEC2 family members in … WebNov 29, 2007 · The C-type lectin-like domain (CTLD) of CLEC2A is most similar to the CTLD of LLT1 ( approximately 60% similarity). Like mouse CLEC2 family members Clr … WebMar 6, 2007 · Function. C-type lectin-like receptor that functions as a platelet receptor for the lymphatic endothelial marker, PDPN ( PubMed: 18215137 ). After ligand activation, … effeminate boys who wear dresses