WebMay 8, 2024 · Implications for Practice Deliver hydration to patients receiving cisplatin therapy to maintain renal function. Include magnesium supplementation, which has … WebApr 10, 2024 · Triple-negative breast cancer (TNBC) is one of the most aggressive forms of breast cancer and constitutes 10–20% of all breast cancer cases. Even though platinum-based drugs such as cisplatin and carboplatin are effective in TNBC patients, their toxicity and development of cancer drug resistance often hamper their clinical use. Hence, novel …
Diuretic Drugs: Nursing Pharmacology Study Guide
Assessment & Drug Effects 1. Obtain baseline ECG and cardiac monitoring during induction therapy because of possible myocarditis or focal irritability. 2. Lab tests: The following tests should be done beforeinitiating every course of therapy and repeated each week during treatment period: serum uric acid, … See more A heavy metal complex with platinum as central atom surrounded by 2 chloride atoms and 2 ammonia molecules in the cis chemical position. Biochemical properties similar to those of bifunctional alkylating agents. Produces … See more Established combination therapy (cisplatin, vinblastine, bleomycin) in patient with metastatic testicular tumors and with doxorubicin for metastatic ovarian tumors following appropriate … See more Cell cycle-nonspecific, i.e., effective throughout the entire cell life cycle. Carcinogenicity has not been fully studied, but other compounds with similar action mechanisms and mutogenicity have been studied. See more History of hypersensitivity to cisplatin or other platinum-containing compounds; impaired renal function; myelosuppression; impaired hearing; history of gout and … See more http://www.robholland.com/Nursing/Drug_Guide/data/monographframes/C085.html cty idc
Cisplatin Uses, Side Effects & Warnings - Drugs.com
WebFeb 1, 2024 · Cisplatin may cause serious kidney problems. Tell you doctor right away if you have blood in urine, change in frequency of urination or amount of urine, difficulty in … WebCisplatin is a platinum-based agent whose nephrotoxicity is thought related to the chloride in the cis position. Cisplatin gains entry into tubular cells via uptake by the OCT-2 … WebREDUCED URINE OUTPUT ANOREXIA NAUSEA VOMITING (uncontrolled by antiemetics) FLUID RETENTION WEIGHT GAIN cty idp